The answer to 'when to treat for mouse' is that the best time to treat for mice is as soon as you notice signs of their presence. Mice can reproduce rapidly, so addressing an infestation early is key to preventing it from getting out of control.
Common signs of mice include droppings, gnaw marks, nests, and scratching or scurrying sounds. If you see these signs, it's time to take action. The most effective treatment is to use a combination of traps, baits, and exclusion methods to eliminate the mice and prevent them from returning.